Übersicht
Unsere Publikationen - seit 2017
- Bien CG. Limbic encephalitis. Handb Neurol 2022; 187:467-487.
- Bien CG. Management of autoimmune encephalitis. Curr Opin Neurol 2021;34:166-171.
- Steriade C, Britton J, Dale RC, Gadoth A, Irani SR, Linnoila J, McKeon A, Shao XQ, Venegas V, Bien CG. Acute symptomatic seizures secondary to autoimmune encephalitis and autoimmune-associated epilepsy: Conceptual definitions. Epilepsia 2020;61:1341-1351.
- Bien CG, Bien CI. Autoimmune encephalitis in children and adolescents. Neurol Res Pract 2020;2:4.
- Bien CG. Diagnosing autoimmune encephalitis based on clinical features and autoantibody findings. Expert Rev Clin Immunol 2019;15:511-527.
- Bien CG, Bien CI (2019) Immundiagnostik autoimmuner Enzephalitiden. Schweizer Zeitschrift für Psychiatrie und Neurologie 02/2019:29-32.
- Bien CG. Grundlagen autoimmuner und paraneoplastischer Enzephalitiden. Nervenarzt 2018;89:934-941.
- Bien CG, Holtkamp M. „Autoimmune Epilepsy“: Encephalitis With Autoantibodies for Epileptologists. Epilepsy Curr 2017;17:134-141.
Tröscher AR …. Bien CG, Temporal lobe epilepsy with GAD antibodies: neurons killed by T cells not by complement membrane attack complex. Brain in press
Ismail FS, Spatola M, Woermann FG, Popkirov S, Jungilligens J, Bien CG, Wellmer J, Schlegel U. Diagnostic challenges in patients with temporal lobe seizures and features of autoimmune limbic encephalitis. Eur J Neurol 2022;29:1303-1310
- Bien CG, Rohleder C, Mueller JK, Bien CI, Koethe D, Leweke FM. Neural autoantibodies in cerebrospinal fluid and serum in clinical high risk for psychosis, first-episode psychosis, and healthy volunteers. Front Psychiatry 2021;12: 654602.
- Rada A, Birnbacher R, Gobbi C, Kurthen M, Ludolph A, Naumann M, Neirich U, von Oertzen TJ, Ransmayr G, Riepe M, Schimmel M, Schwartz O, Surges R, Bien CG. Seizures associated with antibodies against cell surface antigens are acute symptomatic and not indicative of epilepsy: insights from long-term data. J Neurol 2021;268:1059-1069
- Miske R, Scharf M, Stark P, Dietzel H, Bien CI, Borchers C, Kermer P, Ott A, Denno Y, Rochow N, Borowski K, Finke C, Teegen B, Probst C, Komorowski L. Autoantibodies Against the Purkinje Cell Protein RGS8 in Paraneoplastic Cerebellar Syndrome. Neurol Neuroimmunol Neuroinflamm 2021;8.
- Durovic E, Bien C, Bien CG, Isenmann S. MOG antibody-associated encephalitis secondary to Covid-19: case report. BMC Neurol 2021;21:414.
- Loehrer PA, Timmermann L, Pehl A, Bien CI, Pfestroff A, Pedrosa DJ. Rhombencephalitis associated with isolated Zic4-antibodies in Paraneoplastic cerebellar degeneration: a case report. BMC Neurol 2020;20:208.
- Bien CG, Bien CI, Dogan Onugoren M, De Simoni D, Eigler V, Haensch CA, Holtkamp M, Ismail FS, Kurthen M, Melzer N, Mayer K, von Podewils F, Rauschka H, Rossetti AO, Schäbitz WR, Simova O, Witt K, Höftberger R, May TW. Routine diagnostics for neural antibodies, clinical correlates, treatment and functional outcome. J Neurol 2020;267:2101-2114.
- Gruter T, Behrendt V, Bien CI, Gold R, Ayzenberg I. Early immunotherapy is highly effective in IgG1/IgG4 positive IgLON5 disease. J Neurol 2020;267:2151-2153.
- Loehrer PA, Bien CI, Dusoi AE, Timmermann L, Simon OJ. Neurexin-3alpha-associated autoimmune encephalitis: a case report of full recovery after rituximab therapy. Eur J Neurol 2020;27:e91-e93.
- Bien CG, Schänzer A, Dargvainiene J, Dogan-Onugoren M, Woermann F, Strickler A. Co-occurrence of antibodies against dipeptidyl-peptidase-like protein-6 and aquaporin-4 during a case of paraneoplastic encephalitis. Clin Neurol Neurosurg 2020;197:106093.
- Frerker B, Rohde M, Müller S, Bien CG, Köhling R, Kirschstein T. Distinct Effects of Stereotactically Injected Human Cerebrospinal Fluid Containing Glutamic Acid Decarboxylase Antibodies into the Hippocampus of Rats on the Development of Spontaneous Epileptic Activity. Brain Sci 2020;10.
- Bien CG, Braig S, Bien CI. Antibodies against metabotropic glutamate receptor type 1 in a toddler with acute cerebellitis. J Neuroimmunol. 2020;348:577366. doi: 10.1016/j.jneuroim.2020.577366.
- Syrbe S, Stettner GM, Bally J, Borggraefe I, Bien CI, Ferfoglia RI, Huppke P, Kern J, Polster T, Probst-Müller E, Schmid S, Steinfeld R, Strozzi S, Weichselbaum A, Weitz M, Ziegler A, Wandinger KP, Leypoldt F, Bien CG. CASPR2-autoimmunity in children, expanding to mild encephalopathy with hypertension. Neurology 2020;94:e2290-e2301.
- Bien CI, Nehls F, Kollmar R, Weis M, Steinke W, Woermann F, Dalmau J, Bien CG. Identification of adenylate kinase 5 antibodies during routine diagnostics in a tissue-based assay: Three new cases and a review of the literature. J Neuroimmunol 2019;334:576975.
- Nosadini M, Toldo I, Tascini B, Bien CG, Parmeggiani L, De Gaspari P, Zuliani L, Sartori S. LGI1 and CASPR2 autoimmunity in children: Systematic literature review and report of a young girl with Morvan syndrome. J Neuroimmunol 2019;335:577008.
- Koch H, Niturad CE, Theiss S, Bien CG, Elger C, Wandinger KP, Vincent A, Malter M, Kortvelyessy P, Lerche H, Dihne M. In vitro neuronal network activity as a new functional diagnostic system to detect effects of Cerebrospinal fluid from autoimmune encephalitis patients. Sci Rep 2019;9:5591.
- Kersten M, Rabbe T, Blome R, Porath K, Sellmann T, Bien CG, Kohling R, Kirschstein T. Novel Object Recognition in Rats With NMDAR Dysfunction in CA1 After Stereotactic Injection of Anti-NMDAR Encephalitis Cerebrospinal Fluid. Front Neurol 2019;10:586.
- Bien CG. Overinterpretation and Overtreatment of Low-Titer Antibodies Against Contactin-Associated Protein-2. Front Immunol 2018;9:703.
- Garcia-Tarodo S, Datta AN, Ramelli GP, Marechal-Rouiller F, Bien CG, Korff CM. Circulating neural antibodies in unselected children with new-onset seizures. Eur J Paediatr Neurol 2018;22:396-403.
- Thompson J, Bi M, Murchison AG, Makuch M, Bien CG, Chu K, Farooque P, Gelfand JM, Geschwind MD, Hirsch LJ, Somerville E, Lang B, Vincent A, Leite MI, Waters P, Irani SR. The importance of early immunotherapy in patients with faciobrachial dystonic seizures. Brain 2018;141:348-356.
- Mueller SH, Farber A, Pruss H, Melzer N, Golombeck KS, Kumpfel T, Thaler F, Elisak M, Lewerenz J, Kaufmann M, Suhs KW, Ringelstein M, Kellinghaus C, Bien CG, Kraft A, Zettl UK, Ehrlich S, Handreka R, Rostasy K, Then Bergh F, Faiss JH, Lieb W, Franke A, Kuhlenbaumer G, Wandinger KP, Leypoldt F. Genetic predisposition in anti-LGI1 and anti-NMDA receptor encephalitis. Ann Neurol 2018;83:863-869.
- Schimmel M, Frühwald MC, Bien CG. Limbic encephalitis with LGI1 antibodies in a 14-year-old boy. Eur J Paediatr Neurol 2018;22:190-193.
- Muhr P, Goldammer U, Bien CG, Bien C, Sindern E. Schwere Hyponatriamie als Vorbote einer LGI1-Autoimmunenzephalitis. Nervenarzt 2018;89:942-944.
- Elisak M, Krysl D, Hanzalova J, Volna K, Bien CG, Leypoldt F, Marusic P. The prevalence of neural antibodies in temporal lobe epilepsy and the clinical characteristics of seropositive patients. Seizure 2018;63:1-6.
- Blome R, Bach W, Guli X, Porath K, Sellmann T, Bien CG, Kohling R, Kirschstein T. Differentially Altered NMDAR Dependent and Independent Long-Term Potentiation in the CA3 Subfield in a Model of Anti-NMDAR Encephalitis. Front Synaptic Neurosci 2018;10:26.
- Bien CG, Mirzadjanova Z, Baumgartner C, Onugoren MD, Grunwald T, Holtkamp M, Isenmann S, Kermer P, Melzer N, Naumann M, Riepe M, Schabitz WR, von Oertzen TJ, von Podewils F, Rauschka H, May TW. Anti-contactin-associated protein-2 encephalitis: relevance of antibody titres, presentation and outcome. Eur J Neurol 2017;24:175-186.
- Popkirov S, Ayzenberg I, Hahn S, Bauer J, Denno Y, Rieckhoff N, Radzimski C, Hans VH, Berg S, Roghmann F, Noldus J, Bien CG, Skodda S, Wellmer J, Stocker W, Krogias C, Gold R, Schlegel U, Probst C, Komorowski L, Miske R, Kleiter I. Rho-associated protein kinase 2 (ROCK2): a new target of autoimmunity in paraneoplastic encephalitis. Acta Neuropathol Commun 2017;5:40.
- von Podewils F, Suesse M, Geithner J, Gaida B, Wang ZI, Lange J, Dressel A, Grothe M, Kessler C, Langner S, Runge U, Bien CG. Prevalence and outcome of late-onset seizures due to autoimmune etiology: A prospective observational population-based cohort study. Epilepsia 2017;58:1542-1550.
- Popkirov S, Ismail FS, Gronheit W, Kapauer M, Wellmer J, Bien CG. Progressive hippocampal sclerosis after viral encephalitis: Potential role of NMDA receptor antibodies. Seizure 2017;51:6-8.
- Carreno M, Bien CG, Asadi-Pooya AA, Sperling M, Marusic P, Elisak M, Pimentel J, Wehner T, Mohanraj R, Uranga J, Gomez-Ibanez A, Villanueva V, Gil F, Donaire A, Bargallo N, Rumia J, Roldan P, Setoain X, Pintor L, Boget T, Bailles E, Falip M, Aparicio J, Dalmau J, Graus F. Epilepsy surgery in drug resistant temporal lobe epilepsy associated with neuronal antibodies. Epilepsy Res 2017;129:101-105.
- Tröscher AR, Klang A, French M, Quemada-Garrido L, Kneissl SM, Bien CG, Pákozdy Á, Bauer J. Selective Limbic Blood–Brain Barrier Breakdown in a Feline Model of Limbic Encephalitis with LGI1 Antibodies. Front Immunol 2017;8:article 1364.